Walking The Thin Man

In May 2005, I learned that I had developed amyloidosis, a rare protein folding disease. This is my story.

Tuesday, September 06, 2005

Using Immunotherapy against Amyloid?

Immunotherapy is a treatment which works by manipulating your immune system to attack and destroy a foreign agent. Scientists have only recently discovered that this was possible -- it had been thought that the immune system was used to handle viruses and bad bacteria. But now, they've had some preliminary success in getting it to neutralize other things, such as cancer tumors.

Could it be possible that the immune system be trained to attack amyloid. As this lab research article shows, it is certainly possible. But it may take years for this research to translate into a feasible and effective treatment. A clinical trial based on immunotherapy for Alzheimer's patients was inconclusive, but showed that the immune system could have some effect on amyloid.

I don't know much about this topic, but my understanding is that Phase I (and perhaps Phase II) clinical trials are already underway for treating amyloidosis patients via immunotherapy. We are making progress, although it's a slow ride and a long road.

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1 Comments:

At 9/07/2005 10:22 AM , Anonymous Anonymous said...

Great to see that you are back in business...My sympathy to tou over the squirrel issue!
Keep up the good work. We all understand to some degree the ups and downs of your path to wellness...you are very brave.
Carol from ellis PACU

 

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